In many parts of the country whole counties smell of pesticide for a few days every year (and pig-shit another few days, but that’s a different issue)

I’ve lived in some of them, and my mom did a lot of by-hand weed-killer spraying (big plastic refillable jug with sprayer hose & wand) along a mile-plus of fence line, for years. Her generation didn’t really do PPE, so no respirator. Died relatively young of a Parkinson’s-adjacent dementia a little while back. No history of any of that in the family. Hm.