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georgeecollinsyesterday at 2:24 PM4 repliesview on HN

As someone who used to work at the Cognitive Neurophysiology Lab in the Scripts Institute-- doing some work on functional brain image-- I can confirm this was not news even thirty years ago. I guess this is trying to make some point to lay people?


Replies

Aurornisyesterday at 2:27 PM

fMRI has been abused by a lot of researchers, doctors, and authors over the years even though experts in the field knew the reality. It’s worth repeating the challenges of interpreting fMRI data to a wider audience.

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tlbyesterday at 3:20 PM

Are there proposed reasons for increased blood flow to brain regions other than neural activity? Are neurons flushing waste products or something when less active?

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freehorseyesterday at 2:40 PM

The BOLD response (oxygen-neuronal activity coupling) has been pretty much accepted in neuroscience. There have been criticisms about it (non-neuronal contributions, mysteries of negative responses/correlations) but in general it is pretty much accepted.

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jtbaylyyesterday at 2:33 PM

Really? This was known: "there is no generally valid coupling between the oxygen content measured by MRI and neuronal activity"?

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