This segment about the mechanism is simple and very profound. I wonder if any cancer researchers here could comment on its universality across various types of cancers:

"Tumor-Specific Accumulation Mechanism

E. americana selectively accumulates in tumor tissues with zero colonization in normal organs. This remarkable tumor specificity arises from multiple synergistic mechanisms:

Hypoxic Environment: The characteristic hypoxia of tumor tissues promotes anaerobic bacterial proliferation

Immunosuppressive Environment: CD47 protein expressed by cancer cells creates local immunosuppression, forming a permissive niche for bacterial survival

Abnormal Vascular Structure: Tumor vessels are leaky, facilitating bacterial extravasation

Metabolic Abnormalities: Tumor-specific metabolites support selective bacterial growth

Excellent Safety Profile

Comprehensive safety evaluation revealed that E. americana demonstrates:

Rapid blood clearance (half-life ~1.2 hours, completely undetectable at 24 hours)

Zero bacterial colonization in normal organs including liver, spleen, lung, kidney, and heart

Only transient mild inflammatory responses, normalizing within 72 hours

No chronic toxicity during 60-day extended observation"