alt Hacker NewsSo maybe I am too much a layperson here, but even without any direct therapetutic effects, it is pretty remarkable to have an easily scalable mechanism to get self-replicating agents into tumors, but nowhere else, is it not?
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xlbuttplug2 • yesterday at 9:25 AM
Even lay-er person, but maybe the specificity is not that impressive in mice? Perhaps when you scale to more complex animals it is inevitable to see false positives (detrimental effects to healthy cells)?
Yes it is amazing! Solid tumors tend to be poorly oxygenated, as they don't have a good network of blood vessels to supply them. The bacteria in these experiments can only live in low oxygen environments, so they will multiply in the tumor and die in any other part of the body they end up in. It's a clever idea, hopefully it will be successful.