My condolences for your loss. Discussing things in general terms,while having a lived experience must be painful.
There are different cancers, different stages different, different chemos, and of course different people.
Ultimately individual experiences of chemo run the whole gauntlet. At one end it can be little more than a bit of fatigue, at the other end a horrendous nightmare.
Yes, chemo has, as it's goal, a poison function. It sets out to poison you, hopefully killing the cancer first. It's never going to be the "fun" part of treatment.
I'm not a Dr, much less a medical historian. I would be ill equipped to quote specific drugs or dosages. Outcomes however are easily Googled, and those don't seem to be controversial.
I get that improved statistics don't make individual loss any easier.