I work at Graphite, our reviewer is embedded into a bigger-scope code review workflow that substitutes for the GH PR Page.
You might want to look at existing products in this space (Cursor's Bugbot, Graphite's Reviewer FKA Diamond, Greptile, Coderabbit etc.). If you sign up for graphite and link a test github repo, you can see what the flow feels like for yourself.
There are many 1000s of engineers who already have an AI reviewer in their workflow. It comments as a bot in the same way dependabot would. I can't share practical lessons, but I can share that I find it to be practically pretty useful in my day-to-day experience.