Sure, in principle. Have you heard of any company that suffered any significant hardship (say, stock price plummeting, personnel reductions, bankruptcy) because of one of these fines?
Big companies arent suffering any of those. But small businesses and individuals are. Just see the enforcement lists. They are fining small flower shops that sent emails to 20-30 people, some of whom subscribed to it decades ago, then forgot. Or small internet startups for missing one subscription record and whatnot. Like all other corporate moat-building efforts, GDPR has been successful in destroying small businesses in favor of big ones.
Specific to the UK, there's a list of enforcement actions that the Information Commissioners Office (ICO) have taken:
https://ico.org.uk/action-weve-taken/enforcement/
Some went to prison, some were fined £14M and it's a mixture of small fry and big fry.