Famously the golfer Payne Stewart and the total of 6 people on the LearJet 35, died after a sudden loss of cabin pressure incapacitated everyone including the pilots. A system like this, would have detected it and possibly saved them.
I wouldn't expect a whole lot more detail, as that airport is often used by defense contractors like Ball Aerospace, who have a large office nearby.
SafeReturn doesn't detect that as I understand it. It still requires manual activation by one of the passengers.
Even without autoland, I've never understood why there wasn't an emergency system to handle depressurization events when it detects no pilot input. There have been enough ghost flights, even in the last 20 years, that such a system could've saved hundreds of lives. (Helios Air 552) Automatically dropping altitude, or even just changing the transponder to some automatic value, would help.