The current benefit for a Framework is that you can swap out the entire inner/guts without being an expert and everything still works together. Most of the laptops I have provide 2 SO-DIMM slots and a slot for either NVME or SATA for storage.

So for me, there is little value in that in most scenarios. There are a few laptop chassis that I am very fond of and have wished I could "use that chassis with that hardware", but even then I haven't seen Framework chassis designs that give me that impression. I'm not saying they're crappy, but I'm thinking of different types of brushed metal, magnesium alloy stuff, etc.