alt Hacker NewsThe 10x argument for lisp was more compelling when everyone was using C and Fortran instead of JS and python. The contrasts here do seem pretty small.
The real productivity benefit for me is that the ecosystem is so stable and well documented. You can learn it all and keep it in your head.
Guile is an embedded scripting and configuration language. Its competition is Lua. Which is unfortunate for Guile, because it's even less attractive there.