alt Hacker NewsThere appears to be some danger in using NAD+ without the supervision of an experienced physician.
"Pieper emphasized that current over-the-counter NAD+-precursors have been shown in animal models to raise cellular NAD+ to dangerously high levels that promote cancer."
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The chemical the parent comment linked is different.
NAD itself isn’t usually supplemented because it’s broken down by your digestive system. So NAD precursor supplements have been available for a while: NR and NMN specifically. These are the precursors they were talking about.
The actual drug used in this study has a different mechanism of action. It’s not directly available as a supplement, but like the parent commenter discovered you could technically find a chemical supply house to synthesize a tiny quantity of it.
Most people with Alzheimer’s are older and would probably trade having their cognitive abilities back even with increased risk of cancer