THC comes in a plant in the THCa form. CBD comes in CBDa form.
Both are not bioactive by default in their natural form.
All I'll say is go spend a day picking hops without gloves.
There are a large number of cannabinoids at play, some clearly (as in observably and demonstrably) are bioactive in their natural, unheated form.
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None of which is said to endorse the other theory. Just to point out that claiming heat is required is incorrect.
Both degrade into actives over time or exposure to air/sun/warmth, and then into CBN, which is itself active.
All I'll say is go spend a day picking hops without gloves.
There are a large number of cannabinoids at play, some clearly (as in observably and demonstrably) are bioactive in their natural, unheated form.
---
None of which is said to endorse the other theory. Just to point out that claiming heat is required is incorrect.