I think trying to "tune" your kids in any way is asking to be disappointed. My three kids could not be more different and they all have the same mother, grew up in the same house, etc.
If "microRNA" profiles have any influence, I would wager it's very small.
Well that’s just
> No man ever steps in the same river twice, for it's not the same river and he's not the same man
But your kids will likely not have your insights and experiences so “tuning” is another word for broadening their awareness.
When expectations are bundled with trying, then yes disappointment is inevitable. Expectations are not a good reason to not try.
> they all have the same mother, grew up in the same house, etc.
I’m pretty sure the first one didn’t have siblings, and the second only had one. Also their mother is not the same person after raising the first kid, or raising two.
Parenting never have reproducible conditions.