> Also, Occam's Razor would suggest that if it truly worked, surely the very smart people trying to solve this problem would have known about + adopted it.

Please save me from such nonsense. Only naive people believe that. Informed people know that nothing is pursued by big corporations if there isn't big money in it. And there isn't since it's a cheap common product produced around the world.

As a further example, mRNA tech was intentionally rejected, ignored, and not developed for decades. Meanwhile, the false beta-amyloid theory of Alzheimers was purused for over a decade even though it was very clear informed people that it's a dumb theory. People are not as smart as you think they are, not even close.

As for the studies, PMID 27980600 and DOI 10.1016/j.hermed.2024.100875 are a fair start, although the latter is paywalled.