But would you want to run these Win32 software on Linux for daily use? I don't.
Gamers have no other option, and thanks Valve, game studios have no reasons left to bother with native Linux clients.
Just target Windows, business as usual, and let Valve do the hard work.
For making music as much as I love the free audio ecosystem there's some very unique audio plugins with specific sounds that will never be ported. Thankfully bridging with wine works fairly well nowadays.
I knew a guy whose main editor for his day to day was Notepad++ running in Wine.
I use some cool ham radio software, a couple SDR applications, and a lithophane generator for my 3d printer. It all works great, if you have a cool utility or piece of software, why wouldn't you want to?
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Depends on what task you're doing, and to a certain extent how you prefer to do it. For example sure there's plenty of ways to tag/rename media files, but I've yet to find something that matches the power of Mp3tag in a GUI under linux.