Only if I don't need to do anything beyond the built-in widgets and effects of Win32. If I need to do anything beyond that then I don't see me being more productive than if I were using a mature, well documented and actively maintained application runtime like the Web.
That's not really true. Even in the 90s there were large libraries of 3rd party widgets available for Windows that could be drag-and-dropped into VB, Delphi, and even the Visual C++ UI editor. For tasks running the gamut from 3D graphics to interfacing with custom hardware.
The web was a big step backwards for UI design. It was a 30 year detour whose results still suck compared to pre-web UIs.