the main issue with pgvectorscale is that it's not available in RDS :(
I'm considering hosting a separate pg db just to be able to access certain extensions. I am interested in this extension as well as https://wiki.postgresql.org/wiki/Incremental_View_Maintenanc... (also not available on RDS). Then use logical replication for specific data source tables (guess it would need to be DMS).
Yes, RDS seems to really hold PG back on AWS, with all the interesting pg extensions getting released now (pg_lake). It is a share I can't move to other PG vendors because it is a pain in the ass to get all privacy, legal docs in order.