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Psilocybin triggers activity-dependent rewiring of large-scale cortical networks

55 pointsby QueensGambitlast Tuesday at 10:06 PM9 commentsview on HN

Comments

droobyyesterday at 12:17 AM

Obsessive Compulsive Personality disorder (OCPD) is actually way more common than people realize, but it barely gets talked about compared to other mental health issues - and it may even be more of a root cause of things like anxiety, depression. and it is often confused with autism.

What’s interesting about this research is that it points to a possible biological reason why something like psilocybin might help, I.e it seems to loosen really rigid brain patterns. That’s basically the core issue in OCPD: being stuck in overcontrol and perfectionism. It’s not a treatment yet, but it does help explain why psychedelics could be useful for this kind of rigidity.

Would love to see more talk about this - OCPD is often overlooked both by the general public and unfortunately by those impacted by it

N_Lensyesterday at 6:59 AM

Mice are going to have the best mental health in the Universe before the decade is out.

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khelavastryesterday at 4:31 AM

So do 5hT2a receptors when stimulated by DMT-family compounds from INMT during dreamy sleep.

renewiltordyesterday at 9:09 AM

Drugs people want to legalize found to be therapeutically indispensable. Law that specifically allows only these categories found to be unrelated to this mechanism.

NotGManyesterday at 9:46 AM

Many mental illness are now being fully resolved after ~9 to 12 months on a low carb diet.

Not a magic bullet (since I know many idiots will comment who are incapable in thinking in probabilities but only think in black and white), but the fact that some people were fully healed or at least partially improved their life quality is obviously insane progress compared to any medication, which either doesn't work fully or stops working over time.

This channel has more examples: https://www.youtube.com/watch?v=Mlku8oWrQLk

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