I wouldn't apply the usual "but mice" appeal to purity in this case.

For one, the paper specifically studied brain structures that are directly homologous in both mice and humans (retrosplenial cortex). The researchers specifically targeted evolutionarily-conserved circuitry.

Second, there is already human research on the topic, too, and this paper is reporting on a likely mechanism to understand "why" rather than "if." Here's one from a Yale researcher:

https://news.yale.edu/2025/09/23/psilocybin-breakthrough-men...