From https://dukechronicle.com/article/duke-university-facility-a...:

> Duke has a F&A rate of 61.5% with the NIH, which means that for every dollar provided to a Duke faculty member conducting research, an additional 61.5 cents is given to the University to compensate for its F&A costs.

This is not an uncommon overhead rate for a large university, and is competitive with overhead rates at the largest government contractors. That doesn't mean it's entirely reasonable or a sign of an efficient operation.