I play a lot of dota 2 and never really notice anything that is obvious cheat wise. IMO league would probably be fine to do valve level anti cheat, it's even a less twitchy of a game than dota.

FPSs can just say 'the console is the competitive ranked' machine, add mouse + keyboard support and call it a day. But in those games cheaters can really ruin things with aimbots, so maybe it is necessary for the ecosystem, I dunno.

Nobody plays RTSs competitively anymore and low-twitch MMOs need better data hiding for what they send clients so 'cheating' is not relevant.

We are at the point where camera + modded input devices are cheap and easy enough I dunno if anti-cheat matters anymore.