The issue with regime change is whether there's enough political cohesion in a country's population after a despot / autocrat is removed.
"The opposition" is rarely a large and representative enough group to effect national power transition. (Btw, thanks for flagging that incorrectly as affect, Apple)
Especially in multi-ethnic states, most cohesive national identities are forged through extremely popular singular leaders.
Unfortunately, those are exactly the same leaders external regime-change initiators are wary of (too independent).
> Especially in multi-ethnic states, most cohesive national identities are forged through extremely popular singular leaders.
And before you know it you have a genocide on your hands.
This year's winner of the nobel prize is highly organized and ran a parallel election campaign, which was obviously dismissed by the Maduro regime. There is a slim possibility of a peaceful transition given the democratic efforts underway in Venezuela for many years at this point.