Obra Dinn's in-game dithering is also a cool entry for clever, tailor-made dithering in general: https://news.ycombinator.com/item?id=42084080

(there are MANY posts through this large thread, in almost every page, with lots of excellent detail, and lots has been written in general about Obra Dinn. E.g. choosing different algorithms for different surfaces: https://youtu.be/_3qzyAHMoUU?t=2m24s)

For eink: yeah white mixed in is surprisingly easy to pick out compared to other color combinations. It's fine at enough of a distance, so maybe for a picture frame, but pretty rough at a middle reading distance or closer.