This is a good resource, however for about 99.99% of people, you are most likely to just use a foundation model like ChatGPT, Claude, Gemini etc. so this knowledge/training will get you neither here or there. I would suggest you look into another Karpathy's video -- Deep Dive into LLMs like ChatGPT.

https://www.youtube.com/watch?v=7xTGNNLPyMI