I assume the “anti-cheat” he brings up in Doom: The Dark Ages is actually Denuvo, which likely would have some issues running, although a January 2025 post on Phoronix indicates maybe it does work, or Denuvo support is being worked on? [0]

Doom The Dark Ages is a single player game, so I’m not sure who you’d be cheating against, aside from maybe some real Buzz Killington’s saying you’re “cheating Microsoft by pirating it”.

[0] https://www.phoronix.com/news/FEX-Emulator-2501