I actually know about this a bit since it was part of what I was studying with my incomplete PhD.
Isabelle has had the "Sledgehammer" tool for quite awhile [1]. It uses solvers like z3 to search and apply a catalog of proof strategies and then try and construct a proof for your main proof or any remaining subtasks that you have to complete. It's not perfect but it's remarkably useful (even if it does sometimes give you proofs that import like ten different libraries and are hard to read).
I think Coq has Coqhammer but I haven't played with that one yet.
1 Does this mean that Sledgehammer and Coqhammer offer concolic testing based on an input framework (say some computing/math system formalization) for some sort of system execution/evaluation or does this only work for hand-rolled systems/mathematical expressions?
Sorry for my probably senseless questions, as I'm trying to map the computing model of math solvers to common PL semantics. Probably there is better overview literature. I'd like to get an overview of proof system runtime semantics for later usage. 2 Is there an equivalent of fuzz testing (of computing systems) in math, say to construct the general proof framework? 3 Or how are proof frameworks (based on ideas how the proof could work) constructed? 4 Do I understand it correct, that math in proof systems works with term rewrite systems + used theory/logic as computing model of valid representation and operations? How is then the step semantic formally defined?