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micromacrofootyesterday at 2:59 PM1 replyview on HN

> It's insane to me that so many people need these to get off the processed foods killing them in the US.

hah, they're not using them to get off of processed foods... they're using them to reduce the impact of processed foods


Replies

dborehamtoday at 3:45 AM

That's not how these drugs work. Think of it in terms of there being a programmable neural network in the gut (and associated brain I/O areas). This network is designed to get the animal to eat appropriately. But food makers figured out ways (by thousands of years of machine learning) to tweak its weights such that it tells the animal to eat too much. GLP-1 works by un-tweaking those weights (not quite: more like it clamps some of the inputs to the network but the result is the same). So it does indeed work by stopping the consumer from eating as much.