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jacobthesnakobyesterday at 3:07 PM2 repliesview on HN

Which is no surprise to anybody with common sense, the data for discontinuing GLP-1s show exactly the intuitive outcome. Zero diet change, zero habit change for the vast majority of users. Weight loss is accomplished via biochemical tricks to eat less volume of calorie dense junk food, rather than diet substitution. When the artificial appetite suppression ends, volume of the same food increases again leading to weight yo-yo. Plus why start to exercise when you’ve got a magic weight loss drug?

Don’t get me wrong, there are some people using these drugs to get out of a pit of inertia with weight and sedentary lifestyles. But it’s small. GLP-1 drugs will have most users hooked for life because they don’t have the discipline and motivation to maintain the weight loss without it. Cha-Ching!


Replies

rootusrootusyesterday at 4:35 PM

> they don’t have the discipline and motivation to maintain the weight loss

That argument has been tried for years and yet it fails nearly 100% of the time. Should we be trying something different than claiming it's a moral issue? Or is that too scientific?

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WheatMillingtontoday at 3:08 AM

Weight gain/loss is not a matter of motivation and discipline.

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