Looking at the training data I don't think it will know anything.[0] Doubt On the Connexion of the Physical Sciences (1834) is going to have much about QM. While the cut-off is 1900, it seems much of the texts a much closer to 1800 than 1900.
[0] https://github.com/haykgrigo3/TimeCapsuleLLM/blob/main/Copy%...
It doesn’t need to know about QM or reactivity just about the building blocks that led to them. Which were more than around in the year 1900.
In fact you don’t want it to know about them explicitly just have enough background knowledge that you can manage the rest via context.