Its obvious that she was resisting arrest and trying to flee. But as for the ICE agent being in front of the car... barely. I don't believe he genuinely feared for his life, he could have simply stepped out of the way. I think he saw the woman fleeing, figured he was close enough to being in harms way to justify himself, and shot the woman because he was mad at her.

I've been in situations like that in Walmart parking lots, where a car jolts forward and I have to jump out of the way, and maybe I say "That crazy bitch just tried to kill me" but while saying that I understand it to be a hyperbolic albeit justified anger at reckless driving, and that nobody was actually trying to kill me, and shooting the driver in the face instead of diving out of the way would be a suboptimal survival strategy even if homicidal intent was there.