I wonder if there would be some way to create a hyper-local MMO. Let people meet each other from the comfort of their homes and bond over the shared activity of the MMO, and make it so the people you are likely to play with are also in your general geographic region. That way, it would be an easy way to meet people, bond with them, and potentially meet up IRL to take the friendship further.
I think this would be an awesome idea but the main challenge here would be game design and implementation. You'd need a lot of capital and some big ass game studio.