If you have to take the call, and your main concern is desktop client malware...

At a startup a few years ago, since I was the engineering dept., I had to be on a lot of enterprise sales/partnership calls, and much of the time we had to use the other company's favorite videoconferencing software.

Rather than installing those dumpster fire desktop apps on my Linux laptop that had the keys to our kingdom, I expensed an iPad that would be dedicated to random videoconf apps.

We still get violated numerous ways, but at least compartmentalized from the engineering laptop.

(I also used the iPad for passive monitoring of production at night, like a little digital photo frame in my living room, after putting away the work laptop.)