Systemic? It goes way beyond that.

Nature itself ensures that life is short, brutal, violent, and punctuated with horrors. Happiness is a transient state that loses its power if it is present more than part of the time, and joy can only exist in a backdrop of disappointment, or it just becomes another day in the life. We are wired for a life of failure, disappointment, trauma, tragedy, and loss.

That we have wrested a comfortable civilization from these dire circumstances is a great testament to the resolve and resourcefulness of men and women.

We have the great privilege and responsibility of living in this elevated plane, with a long (as biologicaly possible) life lived in relative comfort, and even insulated from the horrors of life by the drapery of civil machinery.

Even so, the only justice in this world is the justice we create ourselves.

The universe owes us nothing, and sometimes collects its debt for the entropy we take from it.