They were more human and relatable in the very early seasons. It was just a bunch of people dicking around trying to run a bar (for the most part).
As time went on, they become more and more awful.
I'd say it has a pretty decent parallel with Breaking Bad. In season 1 almost anyone can relate to and cheers for Walter. By the last season, you hate him and are happy he dies.
I don’t believe most Americans would hate Walter, even at the very end. Americans hate Skylar.
They were committing various felonies in the first season, if I recall. It couldn’t have been more clear that these characters are bad people who will do almost anything to get what they want. The humor lies in the arbitrary and inconsistent boundaries they set for themselves and each other.
Contrast with the initial good intentions of Walt in Breaking Bad. The IASIP characters never had good intentions.