When you print objects with 10's of printers 'tuning your 3D printer' is no longer an option other than to tune it to be 'in spec' You can only tune your designs and the profile for your filament and for a particular model of printer but then all of those have to be close to identical. As soon as you start tweaking your design or filament profile to offset possible issues with the printer you've lost reproducibility.

Incidentally, a lot of the stuff on thingiverse and other similar sites suffers from those kind of issues. They are tuned for PLA on a particular printer without realizing it.