In my mental model, the fundamental problem of reproducibility is that scientists have very hard time to find a penny to fund such research. No one wants to grant “hey I need $1m and 2 years to validate the paper from last year which looks suspicious”.
Until we can change how we fund science on the fundamental level; how we assign grants — it will be indeed very hard problem to deal with.
Funding is definitely a problem, but frankly reproduction is common. If you build off someone else's work (as is the norm) you need to reproduce first.
But without repetition being impactful to your career and the pressure to quickly and constantly push new work, a failure to reproduce is generally considered a reason to move on and tackle a different domain. It takes longer to trace the failure and the bar is higher to counter an existing work. It's much more likely you've made a subtle mistake. It's much more likely the other work had a subtle success. It's much more likely the other work simply wasn't written such that a work could be sufficiently reproduced.
I speak from experience too. I still remember in grad school I was failing to reproduce a work that was the main competitor to the work I had done (I needed to create comparisons). I emailed the author and got no response. Luckily my advisor knew the author's advisor and we got a meeting set up and I got the code. It didn't do what was claimed in the paper and the code structure wasn't what was described either. The result? My work didn't get published and we moved on. The other work was from a top 10 school and the choice was to burn a bridge and put a black mark on my reputation (from someone with far more merit and prestige) or move on.
That type of thing won't change in a reproduction system but needs an open system and open reproduction system as well. Mistakes are common and we shouldn't punish them. The only way to solve these issues is openness
Partially. There's also the issue that some sciences, like biology, are a lot messier & less predicatble than people like to believe.
I often think we should movefrom peer review as "certification" to peer review as "triage", with replication determining how much trust and downstream weight a result earns over time.
In theory, asking grad students and early career folks to run replications would be a great training tool.
But the problem isn’t just funding, it’s time. Successfully running a replication doesn’t get you a publication to help your career.