The "Losers" framing is a bit American, but tragedy has a long history, illustrating the difficulty of being subject to conflicting forces (typically moral, since societies push their interests as such) as a way for understanding to at least explain the pain, taking away the panic and sometimes the isolation. Suffering with some kind of style shows that one is still free, and thus independent of the forces (think Mark Twain humor). Willa Cather's work is more about realizing the big picture itself makes our personal suffering relatively small.