A few years ago, at my company, we would get random TPM crashes every few months on all our machines. You'd be working and the TPM would just disappear and then any apps that rely on it for key retrieval would error out. Even worse, since the TPM chip is always running, neither a reboot nor a shutdown would fix it -- you literally had to pull the plug.

This went on for months. Then one day we had a power outage. Two months later, every single machine failed at the same time. I checked the logs and it was 49 days and few hours since that outage. It didn't take me too long to figure out what the underlying programming error inside the TPM was. At least we could then describe exactly what the problem was to our PC vendor.