Stay tuned, we are about to release a new version of Wasmer with WASIX, that allows for things that can't currently be done with Pyodide:
* Multithreaded support
* Calling subprocesses
* Signals
* Full networking support
* Support for greenlets (say hi to SQLAlchemy!) :)
It requires a small effort in wasmer-js, but it already works fully on the server! :)