> Construction of an infectious horsepox virus vaccine from chemically synthesized DNA fragments
https://journals.plos.org/plosone/article?id=10.1371/journal...
In theory, it's very much doable. We brought back an extinct cowpox virus a while ago using mail-order DNA. Did you know that Smallpox's nucleotide sequence is freely available online?
You're going to have to link that for me because I know the longtermism people are nuts about this, but their actual understanding is pretty poor.
There's a gulf between assembling a vaccine - which is a commonplace technology, and assembling a viable infectious viral particle.
Being able to order all the oligos of a viral sequence isn't even step 1.