Obesity reduction if seen through in the long run will have comparable benefits to smoking cessation. The scale of the win here is hard to overstate.
Then the reductions in lean muscle mass will start to become visible in all cause mortality statistics. This could be a rough ride.
Then why the fuck hasn't the US just added it to Medicare / Medicaid coverage? It makes no sense. These healthcare schemes are costly, and covering this medication would make it... less costly.