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46493168today at 3:34 AM1 replyview on HN

>If you exclude obese individuals

The obesity rate in the US is 40%. The just-overweight rate is 33%. So unless we really ramp up on tackling obesity, the life expectancy is going be dragged down.


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cthalupatoday at 4:25 AM

Universal access to GLP1s would almost certainly effectively end the obesity problem.

SubQ pen injections are something even most people afraid of needles can get used to quite quickly, so even if the pill forms never get to the same efficacy there's really no reason that they couldn't solve it for most everyone once they go generic and become affordable, or become otherwise subsidized. China already produces the APIs in huge quantities for insanely cheap for sale on the black market, so we know that they can be produced for extremely low costs.

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