If the people with access to Room 641A want you, you're toast unless you're ready to make some REALLY big digital lifestyle changes that most people would not be amenable to, because you would have to be extremely paranoid on multiple fronts all the time. That kind of heightened vigilance is exhausting and really not worth it.
Threat modeling: it keeps things realistic.
Sorry for assuming you'd be able to extrapolate from one example. It could be at any level of the funnel from your local machine to the wider Internet. Closer to home: this sort of fingerprinting could defeat things like MAC randomization in a PSK-authed business/university setting if those IT departments had some reason to want to track you.
I once worked at a company where the Security team were very proud of this and all the other tricks they used to catch leakers by figuring out who was on campus, where, at what time, usually via fingerprinting personal devices carried alongside corporate devices.