There's a bunch of stuff coming out about his coordination with Epstein to run pandemic simulations, and a lot of business level stuff going on after Epstein's initial run-ins with the law. That aside if he's on a personal enough level to ask him for antibiotics to sneakily slip his wife, then Bill would definitely know about all the rest.
Really don't have any more room to give these people the benefit of doubt.
If you’re Bill/Melinda and you’re undertaking a massive project to change the world positively, why not take money from Epstein? The public benefit would dwarf whatever benefit Jeff could obtain.