It would destroy the Z80. It's a 32bit, dual core CPU running at 133MHz. Even single cored it'll thrash a Z80. Heck, I bet you could create a drop-in replacement board for the Z80 using an RP2040.
Yes, I understand that, but I wonder about the multiple (obviously there is more to it than clock speed). I chose the Z80 because of its long-standing reputation.
Crazy what you can buy nowadays like the Teensy 4.0 with 600MHz base clock
Granted that's $20 not $1
Note it was possible to use a Z80 to function as a display controller, people used to do it back in the day...
https://archive.org/details/Cheap_Video_Cookbook_Don_Lancast...