IIUC, if you have the source you can recompile said Windows app with LiteBox to statically link in the Windows OS kernel dependencies, so it'll run on any compatible processor regardless of OS (since it won't be making syscalls anymore). It's a unikernel basically.

That's the theory, but I don't know how far LiteBox is along to supporting that workflow.

They say

> It focuses on easy interop of various "North" shims and "South" platforms.

For replacing wine on Linux the "North" would be kernel32 API or similar, the "South" would be Linux sys all API.

However this is meant as a library, thus require linking the Windows program to it and eine is more than the system interface, it has all the GUI parts etc of win32 API