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phil21today at 1:41 AM2 repliesview on HN

Eli Lilly will categorically state it is impossible for the compounders to be using the same API as they are due to being the sole source of manufacturing for it on the planet.

From what I can tell they are technically correct. The FDA approved method of manufacturing the peptide chain is different than the Chinese sources these compounders are sourcing from. It may not make an actual biological difference (and hefty evidence of millions of people on it show there is unlikely to be a material difference) but it’s not the same as a generic medication being approved.

This is about as Wild West as most of us have lived through for the U.S. drug market.


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mullingitovertoday at 1:54 AM

> This is about as Wild West as most of us have lived through for the U.S. drug market.

I don't know about that. I'm old enough to remember The Vaping Panic of 2019, where (medical and/or recreational) cannabis vape liquid was adulterated with Vitamin E acetate in industrial quantities, which caused widespread injury and death. The real cause was called out very quickly (thanks in part to investigative reporting by...WeedMaps[1]), but health departments flailed and spent months blaming it on Juul and teen e-cigarettes. The panic evaporated because right as the public health community realized what was happening, Covid broke out.

To this day, afaik no testing of vapes is required to ensure they don't contain this toxic ingredient.

[1] https://weedmaps.com/news/2019/10/why-vitamin-e-acetate-and-...

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terminalshorttoday at 2:18 AM

In that case I want to see more wild west because this is working fine for me.

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