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marticodetoday at 7:07 AM4 repliesview on HN

> higher caffeinated coffee intake was significantly associated with lower dementia risk (141 vs 330 cases per 100 000 person-years comparing the fourth [highest] quartile of consumption with the first [lowest] quartile; hazard ratio, 0.82 [95% CI, 0.76 to 0.89])

That's a very big difference.


Replies

cultofmetatrontoday at 10:46 AM

Doing lots of cognition heavy tasks also seems to correlate with lower dementia risk; Basicly the premise of "brain workout" apps. Thought I think if you're going to be doing brain exercises, that time would be better spent learning a new langauge or learning math or physics or art.

Incidently, People who study or do a lot of thinking heavy deep work also tend to be coffee addicts. coincidence?

show 1 reply
ticulatedsplinetoday at 1:29 PM

Looking at the chart the difference is even larger. The cohort quartiles have different drinks/day. looking at just the NHS cohort the difference between 0 and 4.5 drinks/day was an incident rate of 354 to 95 per 100k person-years.

xattttoday at 10:48 AM

I wonder if this translates to other stimulant use like amphetamines.

The positive effect may be negated by hypertension induced by said stimulants, which would then lead to organic dementias.

dyauspitrtoday at 7:27 AM

So a 100% reduction in risk? Or is it 50% reduction in risk.