> higher caffeinated coffee intake was significantly associated with lower dementia risk (141 vs 330 cases per 100 000 person-years comparing the fourth [highest] quartile of consumption with the first [lowest] quartile; hazard ratio, 0.82 [95% CI, 0.76 to 0.89])
That's a very big difference.
Looking at the chart the difference is even larger. The cohort quartiles have different drinks/day. looking at just the NHS cohort the difference between 0 and 4.5 drinks/day was an incident rate of 354 to 95 per 100k person-years.
I wonder if this translates to other stimulant use like amphetamines.
The positive effect may be negated by hypertension induced by said stimulants, which would then lead to organic dementias.
So a 100% reduction in risk? Or is it 50% reduction in risk.
Doing lots of cognition heavy tasks also seems to correlate with lower dementia risk; Basicly the premise of "brain workout" apps. Thought I think if you're going to be doing brain exercises, that time would be better spent learning a new langauge or learning math or physics or art.
Incidently, People who study or do a lot of thinking heavy deep work also tend to be coffee addicts. coincidence?