logoalt Hacker News

celltalkyesterday at 7:55 PM1 replyview on HN

It’s a great read but is this really the history of oral peptides?


Replies

abainbridgeyesterday at 8:48 PM

Yep, I think it is. The point is there's almost no history of oral peptides, other than stomachs destroying them.

FTA: "So to summarize the state of the art in oral peptide delivery: there are exactly two FDA-approved products that use permeation enhancers to get peptides into your bloodstream through your GI tract. Both achieve sub-1% bioavailability. Both required over a decade of development, thousands of clinical trial participants, and hundreds of millions of dollars."

show 1 reply