I use ublock origin for that. Some examples from my filters:

     news.ycombinator.com##.subline > [href^="item"]
     news.ycombinator.com###me
     news.ycombinator.com###karma
     news.ycombinator.com###logout
     news.ycombinator.com##td:nth-of-type(3) > .pagetop
     news.ycombinator.com##.score
     www.youtube.com###comments > .ytd-comments.style-scope
     www.youtube.com###chatframe
     www.youtube.com###chat